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MetabolismNucleotidesT Cells

Ep. 39: “Extracellular Nucleotides” Featuring Dr. Henrique Borges da Silva

By October 11, 2022February 8th, 2023No Comments

Henrique Borges da Silva


Dr. Henrique Borges da Silva is an Assistant Professor at the Mayo Clinic in Arizona. His main research focus is determining how extracellular nucleotides affect transcriptional, metabolic, and functional mechanisms of CD8+ T cells in response to viral infections and cancer. He talks about where extracellular ATP comes from, and how there could be a link between ATP and ADP immunological signaling and the powers of caffeine.

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The Immunology Science Round Up

Telomere Transfer in T Cells – An interaction between T cells and antigen presenting cells early in the immune response to viruses may determine how fast T cells decline.

APOE and COVID-19 OutcomesAPOE variants associated with Alzheimer’s disease are also associated with a reduced immune response and increased mortality from COVID-19.

Protecting the Brain from Infection – Scientists identified a new blood-endothelial barrier that separates olfactory mucosa from circulating antibodies.

Bacterial Colonization in the Intestine – An oral bacterium associated with inflammatory bowel disease uses nitrate respiration to colonize the intestine.

Image courtesy of Dr. Henrique Borges da Silva

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