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Ep. 63: “T Cell Tolerance” with Dr. Alice Long

By September 26, 2023No Comments

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Dr. Alice Long is an Associate Member and Principal Investigator at Benaroya Research Institute at Virginia Mason, where her lab focuses on discovering how tolerance is lost in human autoimmunity and how therapy can restore tolerance.

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The Immunology Science Round Up

Insights into B Cell Selection – Antigen-presenting autoreactive B cells play a crucial role in tolerizing T cells and suppressing tissue-specific autoimmune inflammation.

A New Perspective for IBD Management – Researchers discovered a polymorphism encoding a defective fusion protein that is correlated with inflammatory bowel disease severity.

A Neuropeptide in Type 2 Immunity – Scientists show that neuromedin U programs eosinophils to promote mucosal immunity of the small intestine.

Intestinal Antigen Recognition and Humoral Immunity – A new study shows that antigen receptor signaling and cell death resistance control intestinal humoral response zonation.

Image courtesy of Alice Long

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