Cellular CrosstalkImmune RegulationMacrophagesNeutrophils

Ep. 142: “Decoding Cellular Crosstalk” Featuring Dr. Merav Cohen

By October 6, 2026No Comments

Guest:

Dr. Merav Cohen is a Principal Investigator at Tel Aviv University. She discusses how her lab uses single-cell technologies to decode communication between immune cells and their surrounding tissues. She explores how physical interactions can reprogram macrophages and neutrophils, how these cells communicate with tumor cells, and how cellular crosstalk can promote angiogenesis, tumor growth, and cancer progression.

Featured Products and Resources:

The Immunology Science Round Up

Mapping T Cells in Diabetes – Multimodal profiling reveals distinct inflammatory and differentiation states of CD8+ T cells across pancreatic lymph nodes and pancreatic tissue in Type 1 diabetes.

Balancing the Inflammatory Response – IRF2 restrains inflammation by limiting IRF1-driven immune gene expression, revealing a transcriptional switch that regulates innate immune responses.

Interferon Reshapes Stem Cell Fate – Interferon-α reshapes hematopoietic stem cell differentiation in myeloproliferative neoplasms, while disease-causing mutations alter how stem cells respond to treatment.

The Gut–Brain Immune Connection – Gut infections send activated CD4+ T cells to the brain’s borders, where they establish long-lived immune memory against intestinal microbes.

Image courtesy of Dr. Merav Cohen

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