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Guest:
Dr. Robin Orozco is an Assistant Professor at the University of Kansas, where her lab studies how specific allelic variants affect immune responses. She talks about what we can learn from mouse models and the role of PTPN22 in antiviral immunity. (36:48)
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The Immunology Round Up
Skin Infections and Food Allergy – Scientists unraveled mechanisms by which S. aureus skin colonization can aggravate food allergy in atopic dermatitis. (3:10)
Cytotoxic T Cell Dynamics – Nuclear polarization represents a key step during cytotoxic T cell-mediated killing. (11:55)
CRISPR-Boosted CAR T Therapies – Researchers discovered, validated, and biologically characterized CRISPR-boosted CAR T cells that outperform standard CAR T cells. (18:36)
CAR T Cells in Myeloma – New findings reveal differing effects of gene perturbation on CAR T cells and highlight a promising target to generate highly effective CAR T cells for multiple myeloma. (26:40)
Image courtesy of Dr. Robin Orozco
